沪漂脱口秀女演员顾逸白天在杂志社上班，晚上讲脱口秀，没什么远大的野心，就想让台下所有观众都能笑
可某天突然来了个坐在第一排的男观众，顾逸无论如何都逗不笑他，让她异常挫败 顾逸发誓一定要收获男观众的笑脸，一场搞笑女与冷漠男的逗趣罗曼史由此展开 另一群在沪上工作的都市青年为快乐聚集在盎司酒吧，各有打工人的烦恼和无奈，他们爱听脱口秀击中生活痛点的吐槽，幽默调侃举重若轻、却也充满了乐观、励志与豁达的表达也让他们感到快乐、受到启发 顾逸全心投入脱口秀事业，用快乐征服了“笑不出来”的男观众梁代文，收获了美好的爱情，在这个城市扎根下来
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